![](/__local/F/AB/EC/23AA164D8A3D3D5AEB4B936508F_67E38475_D07A.jpg)
邮箱:chenmy2007525@163.com
研究内容:
(1) 利用生物学大数据基于高通量测序和生物信息学分析进行癌症发生发展的相关机制研究;
(2) 基于结构生物学进行病毒核酸聚合酶复制和转录的机理研究。
教育经历:
(1) 2011-09至2016-06,浙江大学,博士(硕博连读)
(2) 2007-09至2011-06,河南农业大学,学士
科研与学术工作经历:
(1) 2019-08至今,湖北工业大学,银河yh8858com,讲师,副教授
(2) 2016-07至2019-02,中国科学院武汉病毒研究所,新发传染病研究中心,助理研究员
在研的科研项目:
(1) 国家重点研发计划项目子课题,2022YFC2604000,复杂现场模拟仿真技术研究,2022-10至2025-09,80万元,主持
(2) 国家自然科学基金青年项目,82303528,HERVs来源的新的lncRNA——HILAL在肝癌发展中的作用及分子机制研究,2024-01至2026-12,30万元,主持
(3) 湖北省自然科学基金青年项目, 2021CFB274,人内源性逆转录病毒在乳腺癌中的激活表达及其功能机制研究, 2021-10至2023-09, 8万元,主持
代表性研究成果:
(1) Chen, M#; Jia, L#; Zheng, X; Han, M; Li, L✳; Zhang, L✳. Ancient Human Endogenous Retroviruses Contribute to Genetic Evolution and Regulate Cancer Cell Type-Specific Gene Expression. Cancer Research, 2022, 82(19): 3457-3473.(中科院一区,IF=11.2)
(2) Wang, Y#; Yang, S#; Wan, Z; Shen, A; Ahmad, MJ;Chen, M✳; Huo L✳, Pan J✳. Chlorothalonil exposure compromised mouse oocyte in vitro maturation through inducing oxidative stress and activating MAPK pathway. Ecotoxicology And Environmental Safety, 2024, 273: 116100.(中科院二区,IF=6.8)
(3) Zhang, L#; Geng, X#; Wang, F#; Tang, J; Ichida, Y; Sharma, A; Jin, S;Chen, M; Tang, M; Pozo, FM; Wang, W; Wang, J; Wozniak, M; Guo, X; Miyagi, M; Jin, F; Xu, Y; Yao, X; Zhang, Y✳. 53BP1 Regulates Heterochromatin through Liquid Phase Separation. Nature Communications, 2022, 13(1): 360.(中科院一区,IF=16.6)
(4) Chen, M#; Guo, X; Zhang, L✳. Unexpected Discovery and Expression of Amphibian Class II Endogenous Retroviruses. Journal of Virology, 2021, 95(3): e01806-20.(中科院二区,IF=5.4)
(5) Chen, M#;Tachedjian, M; Marsh, GA; Cui, J✳; Wang, LF✳.Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections. Frontiers in Microbiology, 2020, 11, 986.(中科院二区,IF=5.2)
(6) Chen, M#; Cui, J✳. Discovery of Endogenous Retroviruses with Mammalian Envelopes in Avian Genomes Uncovers Long-term Bird-mammal Interaction. Virology, 2019, 530: 27-31.(中科院三区,IF=3.7)
(7) Du, Y#;Chen, M; Yang, J; Jia, Y; Han, S; Holmes, EC; Cui, J✳. Molecular Evolution and Emergence of H5N6 Avian Influenza Virus in Central China. Journal of Virology, 2017, 91(12):e00143-17.(中科院二区,IF=5.4)
(8) Wei, X#;Chen, M#; Cui, J✳. Bayesian evolutionary analysis for emerging infectious disease: an exemplified application for H7N9 avian influenza viruses. Science China Life Sciences, 2017, 60, 1392-1395.(中科院一区,IF=9.1)
(9) Wang H#, Zhao Y#,Chen M✳, Cui J✳. Identification of Novel Long Non-coding and Circular RNAs in Human Papillomavirus-Mediated Cervical Cancer.Frontiers in Microbiology,2017, 8, 1720.(中科院二区,IF=5.2)